LIUC

Excluded: Without mutation (n=158)                     Non-EGFR mutation (n=68)

Initial treatment non-squamous NSCLC patients (n=144)

NSCLC patients carrying EGFR mutation (n=224)

NSCLC patients tested by NGS in Second Affiliated Hospital of Nanchang University (n=450) 

Initial treatment non-squamous NSCLC patients with EGFR mutation (n=117)

Excluded: Not Stage IV (n=18)          Untreated (n=9)

Excluded: Non-initial treatment (n=76)                     squamous cell carcinoma(n=4)